Recognized when degree granted on or after February,2011. Annual renewal permission granted for 100 MBBS seats for AY 2024-25
The foundation stone was laid on 16 August 2002 by Chief Minister J. Jayalalitha. The first hospital and college premises were inaugurated on 8 December 2004. In 2006, the first 100 students were admitted to the MBBS programme.

In 2016, an "ultra modern" MRA scanning machine was commissioned at the hospital.[1]

In 2019, Tamil Nadu Police registered a first information report against a first-year medical student of the college for managing to obtain an admission without having appeared for the National Eligibility cum Entrance Test (NEET).[2] The student was alleged to have faked his identity.[3][4] Tamil Nadu police identified announced that they believed that at least six more students had managed to be enrolled in medical colleges through impersonation during the NEET exam.[5][6][7]

In 2021, during the COVID-19 pandemic in India, a video went viral on social media showing bodies left on the floor in the hospital mortuary. The Health Department of the Tamil Nadu government ordered a probe into the apparent violation of COVID-19 protocols.[8]

In 2022, the Madras High Court directed the health secretary of the Tamil Nadu government to investigate the death of a woman who had allegedly died due to medical negligence after a surgery.[9][10]

In July 2023, Dean Dr Meenakshisundaram was suspended by the Tamil Nadu Health and Family Welfare Minister Ma. Subramanian for accepting a bribe from a contractor.[11][12] In October, S. Balashankar, the former head of Paediatrics of the Government Rajaji Hospital was appointed as the Dean by the Government of Tamil Nadu.[13]